Antigen itself antibody: an alternative one-step immunoassay for measuring the anti-idiotypic antibody titer
نویسندگان
چکیده
منابع مشابه
Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay.
Anti-idiotypic antibodies recognize the antigenic determinants of an antibody, thus they can be used as surrogate antigens. Single-domain antibodies from camlid heavy-chain antibodies with the benefit features of small size, thermostability, and ease in expression, are leading candidates to produce anti-idiotypic antibodies. In this work, we constructed an antibody phage library from the mRNA o...
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OBJECTIVE Systemic lupus erythematosus is an autoimmune disease characterized by the production of anti-dsDNA antibody. Because the titer of anti-dsDNA antibody is correlated with disease severity, especially in lupus nephritis, controlling anti-dsDNA antibody production is important in the treatment of SLE. There are many regulatory mechanisms of autoantibody production; one of these is the in...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 2014
ISSN: 0385-5600
DOI: 10.1111/1348-0421.12178